Dialysis and post kidney transplant patients are even more prone to further kidney damage induced by influenza infections, which can lead to secondary bacterial pneumonias, and multi-organ complications, including heart failure. Old age patients and patients who already suffer from any chronic illness such as diabetes, hypertension, cardiac disease or chronic kidney disease constitute the highest risk group. Patients who are critically ill due to influenza can develop Acute kidney failure in up to thirty percent of cases. "Influenza, also known as the flu virus can have a variety of potentially severe effects on kidneys. (Also read: H3N2 Influenza: Signs and symptoms of severe illness to watch out for) H3N2 Influenza: Serious side-effects of the virus on kidney health(HT_PRINT)Īccording to experts, H3N2 Influenza can also seriously damage kidneys especially in elderly and those who already suffer from chronic illnesses like diabetes, hypertension, heart issues or kidney disease. The virus is also causing rise in ICU cases in infants and children below 5 years with many of them reporting breathlessness, cough, fever and pneumonia-like symptoms. Considering H3N2 causes more hospitalisations than other influenza subtypes, one must be cautious and take Covid-like measures like wearing masks, washing hands frequently and follow social distancing to curb its spread. While it is usually known to cause mild disease, vulnerable groups are at risk of severe illness. However, the causality needs further identification.ĬOVID-19 VAERS database acute kidney injury vaccination.After Covid-19, H3N2 Influenza cases are on rise across the country and the virus has already killed two people in India. 008).ĪKI could occur after the COVID-19 vaccines, predominantly in elderly patients. The proportion of patients on dialysis was higher in JANSSEN than in Pfizer-BNT and MODERNA (14.61% vs. Patients in Pfizer-BNT had the worst outcome with 19.78% deaths, following 17.78% in MODERNA and 12.36% in JANSSEN ( p =. The leading cause of post-vaccine AKI was volume depletion (40.78%), followed by sepsis (11.74%). Comorbidities were noticed in 58.83% of the cases and active infections in over 20% of cases. Most patients are elderly, with the highest age in MODERNA (68.41 years) and lowest in JANSSEN (59.75 years). We observed the differences in ages, comorbidities, current illnesses, post-vaccine AKI causes, and time to AKI onset (all p＜.05) among three vaccines. Pfizer-BNT appeared to have a stronger AKI correlation than MODERNA and JANSSEN, based on the highest reporting odds ratio (ROR = 2.15, 95% confidence interval = 1.97, 2.36). The Bayesian and nonproportional analyses explored the correlations between COVID-19 vaccines and AKI. We aimed to investigate the occurrence of post-vaccine AKI reported to the Vaccine Adverse Event Reporting System (VAERS).Īfter data mapping from December 2020 to June 2021, we summarized demographic and clinical features and outcomes of reported cases from three vaccines (Pfizer-BNT, MODERNA, and JANSSEN).
Acute kidney injury (AKI), a rare adverse event, cannot be ignored as millions of doses of coronavirus disease 2019 (COVID-19) vaccinations.
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